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Table 4 Parameters of right ventricular oxygen balance in animals subjected to acute pulmonary hypertension

From: Effects of inhaled iloprost on right ventricular contractility, right ventriculo-vascular coupling and ventricular interdependence: a randomized placebo-controlled trial in an experimental model of acute pulmonary hypertension

Parameter Treatment Baseline Pulmonary hypertension
    Pre-inhalation 5 minutes after inhalation
RCA-PP (mmHg) Iloprost 86 ± 15 61 ± 22* 78 ± 18* †‡
  Control 73 ± 13 51 ± 9* 53 ± 12*
RPP (bpm·mmHg) Iloprost 2,105 ± 342 4,390 ± 766* 2,904 ± 727* †‡
  Control 2,343 ± 816 4,373 ± 997* 4,414 ± 995*
ΔHR·PVA (%) Iloprost 100 ± 0 191 ± 66* 122 ± 29†‡
  Control 100 ± 0 188 ± 44* 197 ± 49*
  1. Values are shown for baseline and in pulmonary hypertension before inhalation and 5 minutes after inhalation of either iloprost or control. For the complete experimental time course, see Additional file 5. Values are expressed as mean ± standard deviation. *P < 0.05 versus baseline; P < 0.05 versus before inhalation; P < 0.05 iloprost versus control (corrected for multiple comparisons). bpm, beats/minute; ΔHR·PVA, changes in the product of heart rate and pressure-volume area; RCA-PP, right coronary artery perfusion pressure; RPP, right ventricular rate pressure product.