Table 2 General haemodynamics in animals subjected to acute pulmonary hypertension

HR (beats/minute)

Iloprost

88 ± 12

112 ± 13*

109 ± 7*

Control

90 ± 16

111 ± 14*

116 ± 15*

CO (l/minute)

Iloprost

4.5 ± 0.5

5.0 ± 0.4

5.6 ± 0.9^‡

Control

4.1 ± 0.9

4.3 ± 0.6

3.9 ± 1.0

SV (ml)

Iloprost

53 ± 6

45 ± 6

51 ± 9^‡

Control

45 ± 13

40 ± 10

35 ± 11

MAP (mmHg)

Iloprost

86 ± 18

69 ± 16*

74 ± 17*

Control

81 ± 7

70 ± 7*

70 ± 11*

LVEDP (mmHg)

Iloprost

11 ± 2

10 ± 2

11 ± 2

Control

11 ± 3

10 ± 3

11 ± 2

RVEDP (mmHg)

Iloprost

10 ± 1

11 ± 1

10 ± 2

Control

10 ± 2

12 ± 1

12 ± 1

SVR (dyn·s/cm⁵)

Iloprost

1,329 ± 324

952 ± 337*

971 ± 406*

Control

1,518 ± 344

1,087 ± 224*

1,257 ± 368*

PVR (dyn·s/cm⁵)

Iloprost

178 ± 79

366 ± 126*

193 ± 66^†‡

Control

210 ± 105

448 ± 168*

464 ± 201*

PVR/SVR

Iloprost

0.14 ± 0.06

0.39 ± 0.07*

0.21 ± 0.09^†

Control

0.13 ± 0.05

0.41 ± 0.12*

0.37 ± 0.12*