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Table 1 Respirator settings and arterial blood gas status in animals subjected to acute pulmonary hypertension

From: Effects of inhaled iloprost on right ventricular contractility, right ventriculo-vascular coupling and ventricular interdependence: a randomized placebo-controlled trial in an experimental model of acute pulmonary hypertension

Parameter Treatment Baseline Pulmonary hypertension
    Pre-inhalation 5 minutes after inhalation
RR (breaths/minute) Iloprost 17 ± 1 17 ± 1 17 ± 1
  Control 17 ± 1 17 ± 1 17 ± 2
VT (ml/kg) Iloprost 10 ± 1 10 ± 1 10 ± 1
  Control 11 ± 1 10 ± 1 10 ± 1
FiO2 (%) Iloprost 37 ± 9 15 ± 2* 15 ± 2*
  Control 35 ± 8 15 ± 1* 15 ± 1*
PO2 (mmHg) Iloprost 161 ± 38 43 ± 4* 43 ± 4*
  Control 161 ± 46 47 ± 5* 44 ± 5*
PCO2 (mmHg) Iloprost 38 ± 2 38 ± 2 41 ± 4
  Control 40 ± 4 37 ± 2 39 ± 3
PH Iloprost 7.46 ± 0.06 7.45 ± 0.07 7.41 ± 0.08
  Control 7.45 ± 0.04 7.47 ± 0.06 7.47 ± 0.04
  1. Values are shown for baseline and in pulmonary hypertension before inhalation and 5 minutes after inhalation of either iloprost or control. For the complete experimental time course, see Additional file 1. Values are expressed as mean ± standard deviation. *P < 0.05 versus baseline (corrected for multiple comparisons). FiO2, fraction of inspired oxygen; P(C)O2, arterial partial pressure of oxygen (carbon dioxide); RR, respiratory rate; VT, tidal volume.