Skip to main content
Figure 3 | Critical Care

Figure 3

From: Effects of inhaled iloprost on right ventricular contractility, right ventriculo-vascular coupling and ventricular interdependence: a randomized placebo-controlled trial in an experimental model of acute pulmonary hypertension

Figure 3

The effects of inhaled iloprost on RV afterload and contractility in animals with PHT. (a) RV afterload is illustrated with effective pulmonary arterial elastance (PA-Ea), and (b) the slopes of the PQ relationships in the PA. RV contractility is shown as (c) Mw and (d) Emax. Data are expressed as mean ± standard deviation. *P < 0.05 versus BL; P < 0.05 versus before inhalation; P < 0.05, ILO versus C (adjusted for multiple comparisons). In addition, P values of the repeated measures analysis of variance are shown separately for the time, group and INT (time × group) effects. BL, baseline; C, control; Ea, effective arterial elastance; Emax, slope of the end-systolic pressure-volume relationship; ILO, iloprost; INT, interaction; Mw, slope of the preload-recruitable stroke work relationship; PHT, pulmonary hypertension; PA, pulmonary artery; PQ, pressure-flow; RV, right ventricular.

Back to article page