Figure 2

The effects of inhaled iloprost on MPAP. The panels show the characteristic experimental time course, with a maximum pulmonary vasodilating effect immediately after inhalation and a duration of action of approximately 30 minutes. The data are expressed as mean ± standard deviation. *P < 0.05 versus BL; †P < 0.05 versus before inhalation; ‡P < 0.05, ILO versus C (adjusted for multiple comparisons). In addition, P values of the repeated measures analysis of variance are shown separately for the time, group and interaction (time × group) effects. BL, baseline; C, control; ILO, iloprost; INT, interaction; MPAP, mean pulmonary artery pressure; PHT, pulmonary hypertension.