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Table 2 Probability of meropenem and imipenem attaining pharmacodynamic targets over entire dosing interval for 30, 50, and 100 percent T>MIC for selected bacterial populations [42]

From: Clinical review: Balancing the therapeutic, safety, and economic issues underlying effective antipseudomonal carbapenem use

    Pharmacodynamic target for entire dosing interval    
  30 percent T > MIC 50 percent T > MIC 100 percent T > MIC
Species Meropenem Imipenem Meropenem Imipenem Meropenem Imipenem
Escherichia coli 100 100 100 100 100 94
Klebsiella pneumoniae 100 100 99 100 99 91
Enterobacter cloacae 100 100 100 100 95 71
Serratia marcescens 99 99 99 99 97 57
Acinetobacter baumannii 83 89 79 88 31 60
Pseudomonas aeruginosa 93 92 87 87 47 27
  1. T>MIC, time greater than minimum inhibitory concentration.