Table 1 Characteristics of patients with severe sepsis
Characteristic | Patients with severe sepsis | P | |
|---|---|---|---|
Nonsurviving (n = 51) | Surviving (n = 40) | ||
Age (years) | 68 (48 to 75) | 57.5 (44.3 to 72.8) | 0.15 |
Males (n [%]) | 29 (56.9) | 27 (67.5) | 0.386 |
Plasma concentration of gelsolin (mg/l; mean ± SE) | 20.9 ± 11.2 | 20.2 ± 12.3 | 0.786 |
Plasma concentration of IL-6 (pg/ml; mean ± SE) | 21.6 ± 11.6 | 19.0 ± 10.0 | 0.59 |
Plasma concentration of IL-10 (pg/ml; mean ± SE) | 68.7 ± 56.0 | 127.3 ± 250.8 | 0.347 |
Plasma concentration of TNF-α (pg/ml; mean ± SE) | 19.2 ± 17.7 | 9.2 ± 5.4 | 0.033 |
Plasma concentration of albumin (g/l; mean ± SE) | 27.5 ± 6.2 | 25.1 ± 6.5 | 0.101 |
APACHE II (median [IQR]) | 24 (17.8 to 27.3) | 17 (12.5 to 22) | <0.001 |
Severe SOFA (median [IQR]) | 9 (6 to 13.3) | 6 (4 to 8) | 0.002 |
Organs with acute dysfunction (n [%]) | |||
Respiratory | 48 (94.1%) | 32 (80%) | 0.054 |
Cardiovascular | 20 (39.2%) | 6 (%) | 0.018 |
Renal | 18 (35.3%) | 6 (15%) | 0.033 |
Haematologic | 20 (39.2%) | 14 (35%) | 0.827 |
Central nervous system | 35 (68.6%) | 23 (57.5%) | 0.283 |
Hepatic | 24 (47.1%) | 14 (35%) | 0.288 |