Variable | All | Cardiac surgery | Trauma | |||
---|---|---|---|---|---|---|
AOX | Placebo | AOX | Placebo | AOX | Placebo | |
Number | 200 | 113 | 66 | |||
Number | 102 | 98 | 57 | 56 | 34 | 32 |
Prior renal failure | 61 (30.5%) | 49 (43.4%)a | 10 (15.1%) | |||
25 | 36 | 20 | 29 | 6 | 4 | |
Acute kidney injury | 66 (33%) | 50 (44.2%)a | 13 (19.7%) | |||
29 (30%) | 36 (37%) | 21 (37%) | 29 (52%)b | 7 | 6 | |
ARF increase of 50 μmol/L | 32 (16%) | 29 (27.5%)a | 3 (15.2%) | |||
15 (15%) | 17 (17% | 13 (23% | 16 (29%) | 2 | 1 | |
ARF increase of 90 μmol/L | 16 (8%) | 15 (13.3%)a | 1 (1.5%) | |||
7 (7%) | 9 (9%) | 6 (11% | 9 (16%) | 1 | 0 | |
CVVH | 7 (3.5%) | 6 (5.3%) | 1 (1.5%) | |||
6 | 1c,d | 5 | 1 | 1 | 0 | |
Persistent renal failure | 11 (5.5%) | 10 (8.8%) | 1 (1.5%) | |||
4 (4%) | 7 (7%) | 3 (5%) | 7 (13%)e | 1 | 0 | |
Ventilator-free days | 26.3 ± 5.5 | 26.6 ± 5.3 | 25.2 ± 6.3 | |||
26.1 ± 5.7 | 26.6 ± 5.2 | 25.9 ± 6.7 | 27.3 ± 3.3e | 25.5 ± 4.6 | 24.9 ± 7.7 | |
Infections (patients with) | 70 | 30 | 30 | |||
36 | 34 | 14 | 16 | 17 | 13 | |
Infectious episodes | 91 | 39 | 39 | |||
45 | 46 | 19 | 20 | 21 | 18 | |
Pneumonia episodes | 30 | 16 | 14 | |||
14 | 16 | 7 | 9 | 7 | 7 | |
Length of stay, days | ||||||
In the ICU | 5.6 ± 5.5 | 5.2 ± 5.1 | 6.3 ± 6.5 | |||
5.8 ± 5.4 | 5.4 ± 5.7 | 5.8 ± 6.0 | 4.7 ± 4.0 | 5.8 ± 4.4 | 6.8 ± 8.3 | |
In intermediate care | 5.0 ± 5.5 | 3.6 ± 3.5 | 6.5 ± 7.2 | |||
4.5 ± 4.9 | 5.5 ± 6.0 | 3.3 ± 4.2 | 3.4 ± 4.1 | 5.9 ± 7.1 | 7.1 ± 7.4 | |
In the hospital | 24 ± 20 | 19 ± 13 | 32 ± 22 | |||
23 ± 20 | 26 ± 20 | 20 ± 14 | 19 ± 13 | 26 ± 19 | 39 ± 24f | |
Deaths | ||||||
In the ICU | 14 (7%) | 11 (9.7%) | 2 (3%) | |||
8 | 5 | 6 | 5 | 2 | 0g | |
In hospital | 23 (11.5%) | 12 (10.6%) | 8 (12.1%) | |||
14 | 9 | 8 | 6 | 6 | 2g | |
At 3 months | 25 (12.5%) | 16 (14.2%) | 8 (12.1%) | |||
14 | 11 | 8 | 8 | 6 | 2g |