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Table 4 Outcome variables with detail of cardiac and trauma patients

From: Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients

Variable

All

Cardiac surgery

Trauma

 

AOX

Placebo

AOX

Placebo

AOX

Placebo

Number

200

113

66

Number

102

98

57

56

34

32

Prior renal failure

61 (30.5%)

49 (43.4%)a

10 (15.1%)

 

25

36

20

29

6

4

Acute kidney injury

66 (33%)

50 (44.2%)a

13 (19.7%)

 

29 (30%)

36 (37%)

21 (37%)

29 (52%)b

7

6

ARF increase of 50 μmol/L

32 (16%)

29 (27.5%)a

3 (15.2%)

 

15 (15%)

17 (17%

13 (23%

16 (29%)

2

1

ARF increase of 90 μmol/L

16 (8%)

15 (13.3%)a

1 (1.5%)

 

7 (7%)

9 (9%)

6 (11%

9 (16%)

1

0

CVVH

7 (3.5%)

6 (5.3%)

1 (1.5%)

 

6

1c,d

5

1

1

0

Persistent renal failure

11 (5.5%)

10 (8.8%)

1 (1.5%)

 

4 (4%)

7 (7%)

3 (5%)

7 (13%)e

1

0

Ventilator-free days

26.3 ± 5.5

26.6 ± 5.3

25.2 ± 6.3

 

26.1 ± 5.7

26.6 ± 5.2

25.9 ± 6.7

27.3 ± 3.3e

25.5 ± 4.6

24.9 ± 7.7

Infections (patients with)

70

30

30

 

36

34

14

16

17

13

Infectious episodes

91

39

39

 

45

46

19

20

21

18

Pneumonia episodes

30

16

14

 

14

16

7

9

7

7

Length of stay, days

      

In the ICU

5.6 ± 5.5

5.2 ± 5.1

6.3 ± 6.5

 

5.8 ± 5.4

5.4 ± 5.7

5.8 ± 6.0

4.7 ± 4.0

5.8 ± 4.4

6.8 ± 8.3

In intermediate care

5.0 ± 5.5

3.6 ± 3.5

6.5 ± 7.2

 

4.5 ± 4.9

5.5 ± 6.0

3.3 ± 4.2

3.4 ± 4.1

5.9 ± 7.1

7.1 ± 7.4

In the hospital

24 ± 20

19 ± 13

32 ± 22

 

23 ± 20

26 ± 20

20 ± 14

19 ± 13

26 ± 19

39 ± 24f

Deaths

      

In the ICU

14 (7%)

11 (9.7%)

2 (3%)

 

8

5

6

5

2

0g

In hospital

23 (11.5%)

12 (10.6%)

8 (12.1%)

 

14

9

8

6

6

2g

At 3 months

25 (12.5%)

16 (14.2%)

8 (12.1%)

 

14

11

8

8

6

2g

  1. Data are presented as number (percentage) and mean ± standard deviation. aP < 0.001. bP = 0.109. cP = 0.05. dSee comment in Results section. eP = 0.17. fP = 0.016. gP = 0.16. Superscript a refers to comparison between diagnostic categories. Superscripts b, c, e, f, and g refer to comparison between antioxidant (AOX) and placebo groups. ARF, acute renal failure; CVVH, continuous veno-venous hemofiltration; ICU, intensive care unit.