Influence of early antioxidant supplements on clinical evolution and organ function in critically ill cardiac surgery, major trauma, and subarachnoid hemorrhage patients

Table 3 Specific severity indices in the trauma patients on enrollment, according to presence of brain injury

Trauma (n = 66)	AOX	Placebo	P value
Number	34	32
Injury Severity Score, all	30.1 ± 9.8	28.3 ± 10.4	NS
Brain injury (n = 39; 20/19)	31.0 ± 11.0	28.7 ± 11.9	NS
No brain injury (n = 27; 14/13)	28.9 ± 7.9	27.6 ± 8.1	NS
Injury Severity Score brain, in brain-injured	14.5 ± 4.9	10.8 ± 4.5	0. 019
Glasgow Coma Scale score initial, all	10.4 ± 4.9	11.8 ± 4.3	0.16
Brain injury	7.4 ± 4.3	9.7 ± 4.8	0.11
No brain injury	14.6 ± 0.6	14.8 ± 0.8	NS
SAPS II	39.9 ± 17.0	31.1 ± 12.2	0.04
SOFA score, neuro section	1.62 ± 1.7	0.97 ± 1.2	0.085
Brain injury	2.5 ± 1.6	1.38 ± 1.2	0.012
No brain injury	0.2 ± 0.4	0.2 ± 0.6	NS

Data are presented as mean ± standard deviation. P values refer to comparison between the antioxidant (AOX) and placebo groups. NS, not significant; SAPS, Simplified Acute Physiology Score; SOFA, sequential organ failure assessment.

ISSN: 1364-8535