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Table 4 Performance characteristics of urinary interleukin-18 (IL-18) according to different RIFLE criteria

From: Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: a prospective observational cohort study

Variables AUC-ROCC (95% CI) P value
RIFLE R or worse (R: n = 31 + I: n = 13 + F: n = 6)   
   Urinary IL-18 on arrival in the intensive care unit 0.61 (0.48–0.74) 0.12
   Urinary IL-18 at 24 hours after cardiopulmonary bypass 0.57 (0.43–0.71) 0.30
RIFLE I or worse (I: n = 13 + F: n = 6)   
   Urinary IL-18 on arrival in the intensive care unit 0.52 (0.38–0.68) 0.35
   Urinary IL-18 at 24 hours after cardiopulmonary bypass 0.58 (0.43–0.73) 0.28
  1. For RIFLE classes [14], serum creatinine increases within 120 hours postoperatively and urinary output during the first 24 hours postoperatively. AUC-ROCC, area under the curve for the receiver operating characteristic curve; CI, confidence interval; RIFLE, Risk of renal dysfunction, Injury to the kidney, Failure of kidney function, Loss of kidney function, and End-stage kidney disease; RIFLE F, RIFLE Failure; RIFLE I, RIFLE Injury; RIFLE R, RIFLE Risk.