Skip to main content

Table 1 Preoperative characteristics of and intraoperative interventions in patients

From: Urinary interleukin-18 does not predict acute kidney injury after adult cardiac surgery: a prospective observational cohort study

Characteristics

AKI (n = 20)

No AKI (n = 80)

P value

Demographic data

   

   Age, years

75.3 ± 4.1

68.1 ± 9.7

<0.001

   Female, number (percentage)

6 (30.0)

33 (41.0)

0.36

   Body mass index

29.7 ± 4.3

27.4 ± 4.5

0.045

Comorbidities

   

   Preoperative serum creatinine, μmol/L

96.1 ± 31.6

89.4 ± 24.0

0.30

   Preoperative estimated glomerular filtration rate < 60 mL/minute, number (percentage)

8 (40.0)

19 (23.8)

0.14

   Left ventricular dysfunction (ejection fraction < 40%), number (percentage)

7 (35.0)

18 (22.5)

0.25

   Arterial hypertension, number (percentage)

20 (100.0)

64 (80.0)

0.029

   Hypercholesterolemia, number (percentage)

16 (80.0)

46 (57.5)

0.06

   Atrial fibrillation, number (percentage)

10 (50.0)

16 (20.0)

0.006

   Myocardial infarction (within 6 months preoperatively), number (percentage)

7 (35.0)

13 (16.3)

0.06

   Chronic obstructive pulmonary disease, number (percentage)

6 (30.0)

8 (10.0)

0.021

   Peripheral vascular disease, number (percentage)

4 (20.0)

2 (2.5)

0.013

   Diabetes mellitus, number (percentage)a

8 (40.0)

20 (25.0)

0.18

Intervention

   

   Coronary artery bypass grafting surgery, number (percentage)

7 (35.0)

18 (22.5)

0.25

   Valvular surgery, number (percentage)

7 (35.0)

45 (56.3)

0.09

   Simultaneous coronary revascularisation and valve surgery, number (percentage)

6 (30.0)

11 (13.8)

0.08

   Duration of cardiopulmonary bypass (minutes)

147.0 ± 31.6

136.0 ± 41.0

0.20

   Fluid intake, 0–24 hours, mLb

5,500 ± 1,900

5,150 ± 1,250

0.44

   Urine output, 0–24 hours, mL

3,350 ± 1,050

3,990 ± 1,500

0.034

   Furosemide dose, 0–24 hours, mg

133.9 ± 168.7

30.9 ± 34.8

<0.001

Outcomes

   

   Need for renal replacement therapy or died during hospital stay, number (percentage)

4 (20.0)

1 (1.3)

0.005

   Ventilation, days

2.4 ± 3.1

0.9 ± 0.8

0.010

   Length of stay in the intensive care unit, days

6.3 ± 7.1

2.3 ± 2.1

0.012

   Length of stay in hospital, days

16.2 ± 13.8

9.5 ± 4.7

0.026

  1. aDiabetes mellitus includes patients on antidiabetic medication and on insulin. bCrystalloids, colloids, and oral fluids from the commencement of cardiopulmonary bypass to 24 hours thereafter. AKI, acute kidney injury.