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Figure 4 | Critical Care

Figure 4

From: Bench-to-bedside review: Avoiding pitfalls in critical care meta-analysis – funnel plots, risk estimates, types of heterogeneity, baseline risk and the ecologic fallacy

Figure 4

Ecological fallacy in meta-regression. Hypothetical relationships between age and treatment effect both within trials (represented by lines) and between trials (represented by dots). Upper: treatment effect is related to age within each trial, but is not related to the mean age across trials. Lower: relationship occurs across trials, but not within trials. Stat Med, How should meta-regression analyses be undertaken and interpreted?, Thompson SG, Higgins JP, Copyright© 2002 John Wiley & Sons Limited. Reproduced with permission [24].

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Critical Care

ISSN: 1364-8535