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Table 4 Patient baseline characteristics and mortality according to admission status

From: Association of HMGB1 polymorphisms with outcome in patients with systemic inflammatory response syndrome

Variable

SIRS without infection group

Sepsis group

Severe sepsis group

Septic shock group

Number of patients (%)

63 (26.4%)

24 (10.0%)

87 (36.4%)

65 (27.2%)

Age (years)

58.5 ± 18.2

54.8 ± 15.4

63.1 ± 14.9

64.1 ± 15.1

Type of admission

    

   Acute surgery

33 (13.8)

11 (4.6)

32 (13.4)

26 (10.9)

   Elective surgery

4 (1.7)

1 (0.4)

2 (0.8)

0 (0)

   Medical

26 (10.9)

12 (5.0)

53 (22.2)

39 (16.3)

Chronic disease

    

   Metastatic cancer

0

0

0

1

   Hematological malignancy

1

0

2

0

SAPS II scorea

32.7 ± 15.8

23.4 ± 8.4

40.4 ± 12.1

45.7 ± 14.4

PaO2/FiO2 ratioa

183 ± 93

351 ± 53

152 ± 89

137 ± 82

Serum HMGB1 (ng/μl)

0.94 ± 1.81

1.49 ± 3.15

1.38 ± 2.73

1.79 ± 4.00

Number of SIRS criteriaa

    

   2

31 (13.0)

8 (3.3)

17 (7.1)

5 (2.1)

   3

20 (8.4)

8 (3.3)

31 (13.0)

19 (7.9)

   4

12 (5.0)

8 (3.3)

39 (16.3)

41 (17.2)

Overall survival (%)

    

   Day 28

87

88

62

65

   Follow-up time

52

71

25

41

  1. Data presented as n (%), mean ± standard deviation or percentage. aComparison of systemic inflammatory response syndrome (SIRS) without infection versus sepsis, severe sepsis and shock, and comparison of sepsis versus severe sepsis versus septic shock, P < 0.01. HMGB1, high mobility group box 1 protein; PaO2/FiO2 = ratio between partial pressure of oxygen and fraction of inspired oxygen; SAPS II, Simplified Acute Physiology Score II.