Variable | SIRS without infection group | Sepsis group | Severe sepsis group | Septic shock group |
---|---|---|---|---|
Number of patients (%) | 63 (26.4%) | 24 (10.0%) | 87 (36.4%) | 65 (27.2%) |
Age (years) | 58.5 ± 18.2 | 54.8 ± 15.4 | 63.1 ± 14.9 | 64.1 ± 15.1 |
Type of admission | ||||
Acute surgery | 33 (13.8) | 11 (4.6) | 32 (13.4) | 26 (10.9) |
Elective surgery | 4 (1.7) | 1 (0.4) | 2 (0.8) | 0 (0) |
Medical | 26 (10.9) | 12 (5.0) | 53 (22.2) | 39 (16.3) |
Chronic disease | ||||
Metastatic cancer | 0 | 0 | 0 | 1 |
Hematological malignancy | 1 | 0 | 2 | 0 |
SAPS II scorea | 32.7 ± 15.8 | 23.4 ± 8.4 | 40.4 ± 12.1 | 45.7 ± 14.4 |
PaO2/FiO2 ratioa | 183 ± 93 | 351 ± 53 | 152 ± 89 | 137 ± 82 |
Serum HMGB1 (ng/μl) | 0.94 ± 1.81 | 1.49 ± 3.15 | 1.38 ± 2.73 | 1.79 ± 4.00 |
Number of SIRS criteriaa | ||||
2 | 31 (13.0) | 8 (3.3) | 17 (7.1) | 5 (2.1) |
3 | 20 (8.4) | 8 (3.3) | 31 (13.0) | 19 (7.9) |
4 | 12 (5.0) | 8 (3.3) | 39 (16.3) | 41 (17.2) |
Overall survival (%) | ||||
Day 28 | 87 | 88 | 62 | 65 |
Follow-up time | 52 | 71 | 25 | 41 |