Table 1 Baseline characteristics of the patient population and results of the univariate analysis
Control | Hypothermia | P value | |
|---|---|---|---|
(n = 74) | (n = 52) | ||
Age, years | 63.8 (52.8–72.0) | 62.6 (50.7–71.4) | 0.776 |
Gender | |||
Female | 21 (28.4) | 9 (17.3) | 0.221 |
Male | 53 (71.6) | 43 (82.7) | |
APACHE II score | 25.0 (20.0–30.0) | 30.5 (22.5–33.0) | 0.015 |
Cardiac arrest | |||
Shockable rhythm | 43 (58.1) | 34 (65.4) | 0.523 |
Non-shockable rhythm | 31 (41.9) | 18 (34.6) | |
Cause of cardiac arrest | |||
Acute myocardial infarction | 47 (63.5) | 31 (59.6) | |
Primary arrhythmia | 12 (16.2) | 13 (25) | |
Respiratory | 12 (16.2) | 8 (15.4) | |
Other | 3 (4.1) | 0 | |
Bystander CPR | |||
Yes | 12 (16.2) | 16 (30.8) | 0.086 |
No | 62 (83.8) | 36 (69.2) | |
Time to ROSC, minutes | 20 (18–25) | 20 (14–22) | 0.230 |
Total epinephrine dose, mg | 3.0 (2.0–4.0) | 2.75 (0.8–3.1) | 0.106 |
Length of ICU stay, days | |||
All patients | 15 (7–26) | 13 (8–26) | 0.947 |
Non-survivors | 7 (5–10) | 9 (6–22) | 0.259 |
Survivors | 21 (15–30) | 14 (8–26) | 0.017 |
Time on ventilator, hours | |||
All patients | 217 (139–353) | 220 (124–428) | 1 |
Non-survivors | 165 (104–210) | 221 (133–365) | 0.219 |
Survivors | 328 (208–461) | 219 (125–447) | 0.113 |
Leukocytes at day 3,/nL | 11.0 (8.7–13.6) | 12.2 (8.3–14.1) | 0.91 |
C-reactive protein at day 3, mg/dL | 12.7 (7.5–16.0) | 14.5 (8.7–21.1) | 0.33 |
Radiological signs of pneumonia | 8 (10.8) | 10 (19.2) | 0.205 |
CPC at ICU discharge | |||
1 – good recovery | 8 (10.8) | 22 (42.3) | |
2 – moderate disability | 9 (12.2) | 10 (19.2) | |
3 – severe disability | 3 (4.1) | 2 (3.8) | |
4 – vegetative state | 23 (31.1) | 3 (5.8) | |
5 – death | 31 (41.9) | 15 (28.8) | |
CPC 1–2 versus 3–5 | |||
CPC 1–2 | 17 (23.0) | 32 (61.5) | <0.001 |
CPC 3–5 | 57 (77.0) | 20 (38.5) | |
Died during hospital stay | |||
Yes | 31 (41.9) | 15 (28.8) | 0.190 |
No | 43 (58.1) | 37 (71.2) |