Admission characteristic | Placebo (n = 77) | Progesterone (n = 82) | P value |
---|---|---|---|
Males | 57 (74) | 58 (70) | 0.64 |
Females | 20 (25) | 24 (29) | 0.64 |
Mean (standard deviation) age (years) | 31 (9) | 30 (11) | 0.52 |
Mean (standard deviation) time injury to administration (hours) | 3.65 (1.46) | 3.80 (2.03) | 0.59 |
Mean (standard deviation) qualifying Glasgow Coma Scale score | 6.1 (1.3) | 6.0 (1.8) | 0.68 |
Glasgow Coma Scale 3 to 5 | 20 (25) | 22 (26) | 0.90 |
Mechanism of injury | Â | Â | Â |
   Motor vehicle | 62 (80) | 63 (76) | 0.57 |
   Fall | 8 (10) | 10 (12) | 0.71 |
   Assault | 4 (5) | 7 (8) | 0.40 |
   Other | 3 (3) | 2 (2) | 0.59 |
   Surgical procedures | 24 (31) | 22 (26) | 0.54 |
Pupillary response | Â | Â | Â |
   Bilaterally normal | 26 (33) | 26 (31) | 0.78 |
   Abnormal | 51 (66) | 56 (68) | 0.78 |
Marshall computerized tomography scan classification | Â | Â | Â |
   I | 0 | 0 |  |
   II | 9 (11) | 7 (8) | 0.50 |
   III | 22 (28) | 28 (34) | 0.44 |
   IV | 13 (16) | 12 (14) | 0.69 |
   V | 24 (31) | 22 (26) | 0.54 |
   VI | 9 (11) | 13 (15) | 0.44 |