Table 2 Effect of melatonin on nocturnal sleep efficiency on nights 3 and 4, using different outcome measures
| Â | Bispectral index sleep efficiency index (95% confidence interval) | |||
|---|---|---|---|---|
Sleep measurement method | Placebo group | Melatonin group | Difference | P value of the difference |
Primary analysis | ||||
Bispectral index | 0.26 (0.17 to 0.36) | 0.39 (0.27 to 0.51) | 0.12 (-0.02 to 0.27) | 0.09 |
Secondary analysis | ||||
Actigraphy | 0.75 (0.67 to 0.83) | 0.73 (0.53 to 0.93) | -0.02 (-0.24 to 0.20) | 0.84 |
Nurse assessment | 0.51 (0.35 to 0.68) | 0.45 (0.26 to 0.64) | -0.06 (-0.29 to 0.17) | 0.58 |
Patient assessment (RCSQ) | 0.50 (0.43 to 0.58) | 0.41 (0.24 to 0.59) | -0.09 (-0.28 to 0.09) | 0.32 |