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Table 2 Summary comparison of SPRINT and retrospective glycaemic control

From: Implementation and evaluation of the SPRINT protocol for tight glycaemic control in critically ill patients: a clinical practice change

Overall cohort data Retrospective SPRINT P value
   Number of patients 413 371  
   Hours of control 43,447 44,769  
   Total BG measurements 13,162 27,664  
   BG mean (log-normal), mmol/L 7.2 6.0 <0.01
   BG standard deviation (log-normal), mmol/L 2.4 1.5  
   Percentage of measurements between    
4.4 and 6.1 mmol/L 30.0% 53.9% <0.01
   Percentage of measurements less than    
4.4 mmol/L 6.5% 9.0% <0.01
4.0 mmol/L 3.8% 3.8% 0.97
2.2 mmol/L 0.2% 0.1% <0.01
   Mean insulin usage, U/hour 1.2 2.8 <0.01
   Mean nutrition rate    
During periods of feeding, kcal/day 1,599 1,283 <0.01
Entire duration of SPRINT usage, kcal/day - 1,014  
   Mean percentage of goal feed - 66.1%  
Per-patient data    
   Hours of control 49 (19–140) 53 (19–146) 0.24
   Number of BG measurements 15 (6–40) 37 (17–97) <0.01
   BG mean (log-normal), mmol/L 7.4 (6.6–8.3) 6.0 (5.5–6.6) <0.01
   BG standard deviation (log-normal), mmol/L 1.6 (1.2–2.4) 1.3 (1.0–1.8) <0.01
   Percentage of patients <6.1 mmol/L 74.3% 96.0% <0.01
   Insulin usage, U/hour 0.9 (0.1–1.6) 2.6 (2.1–3.3) <0.01
   Nutrition rate    
During periods of feeding, kcal/day 908 (0–1,608) 936 (0–1,308) 0.68
Entire duration of SPRINT usage, kcal/day - 709 (0–1,167)  
   Percentage of goal feed - 49.7 (0.0–70.8)  
  1. Per-patient data are expressed as median (interquartile range) as appropriate. BG, blood glucose concentration; SPRINT, Specialised Relative Insulin Nutrition Tables.