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Table 1 Comparison of SPRINT and retrospective cohort baseline variables

From: Implementation and evaluation of the SPRINT protocol for tight glycaemic control in critically ill patients: a clinical practice change

 

Overall

 

Retrospective

SPRINT

P value

Total patients

413

 

371

  

Age, years

64 (53–74)

 

65 (49–74)

 

0.53

Percentage of males

59.1%

 

63.6%

 

0.19

APACHE II score

18 (15–23)

 

18 (15–24)

 

0.50

APACHE II risk of death

28.5% (14.2%-49.7%)

 

25.7% (13.1%-49.4%)

 

0.39

Diabetic history

71 (17.2%)

 

62 (16.7%)

 

0.86

APACHE III diagnosis

     

Operative

Number of patients

Percentage

Number of patients

Percentage

P value

   Cardiovascular

99

24%

76

20%

0.24

   Respiratory

10

2%

9

2%

1.00

   Gastrointestinal

53

13%

60

16%

0.18

   Neurological

9

2%

7

2%

0.77

   Trauma

8

2%

14

4%

0.12

   Other (renal, metabolic, orthopaedic)

4

1%

4

1%

0.88

Non-operative

Number of patients

Percentage

Number of patients

Percentage

P value

   Cardiovascular

41

10%

39

11%

0.79

   Respiratory

77

19%

66

18%

0.76

   Gastrointestinal

7

2%

10

3%

0.34

   Neurological

33

8%

20

5%

0.15

   Trauma

29

7%

32

9%

0.40

   Sepsis

29

7%

17

5%

0.15

   Other (renal, metabolic, orthopaedic)

14

3%

17

5%

0.39

  1. Data are expressed as median (interquartile range) where appropriate. P values computed using chi-square and Mann-Whitney U tests where appropriate. APACHE, Acute Physiology And Chronic Health Evaluation; SPRINT, Specialised Relative Insulin Nutrition Tables.