|  | Sample size | Univariate odds ratio | ||
---|---|---|---|---|---|
Measure | Cut-offa | Higher risk | Lower risk | Odds ratio (95% CI) | P |
Protein C (%) | <42 | 240 | 578 | 4.63 (3.35 to 6.41) | <0.0001 |
Protein S (%) | <42 | 297 | 521 | 3.25 (2.38 to 4.43) | <0.0001 |
Antithrombin III (%) | <60 | 306 | 512 | 4.17 (3.05 to 5.71) | <0.0001 |
Interleukin-6 (pg/ml) | ≥185.6 | 264 | 563 | 7.27 (5.23 to 10.11) | <0.0001 |
Prothrombin time (seconds) | ≥18.4 | 233 | 585 | 6.13 (4.40 to 8.56) | <0.0001 |
D-dimer (μg/ml) | ≥4.63 | 408 | 410 | 2.13 (1.57 to 2.89) | <0.0001 |
Cardiovascular SOFA | ≥3 | 301 | 539 | 7.32 (5.28 to 10.13) | <0.0001 |
Respiratory SOFA | ≥3 | 358 | 482 | 3.36 (2.48 to 4.56) | <0.0001 |
Renal SOFA | ≥1 | 335 | 505 | 4.82 (3.52 to 6.59) | <0.0001 |
Hematologic SOFA | ≥2 | 252 | 588 | 3.42 (2.50 to 4.68) | <0.0001 |
Hepatic SOFA | ≥1 | 256 | 573 | 2.11 (1.55 to 2.89) | <0.0001 |