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Figure 3 | Critical Care

Figure 3

From: Protein C: a potential biomarker in severe sepsis and a possible tool for monitoring treatment with drotrecogin alfa (activated)

Figure 3

Mortality from PROWESS and ENHANCE based on end-of-infusion PC levels by categories. The protein C (PC) categories were normal (> 80%), deficient (41% to 80%), and severely deficient (< 40%). The number in each column is the total number of patients in each category. Patients were included if they had a baseline PC measure. Day 4 PC was classified as end of infusion. If day 4 measurement was not available, last observation carried forward values were used for classification. These data were reported by Vangerow and coworkers [42]. ENHANCE, Extended Evaluation of Recombinant Activated Protein C; PROWESS, Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis.

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