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Table 2 Multivariate analysis of cause-specific hazard ratios for the acquisition of nosocomial pneumonia (model 1)

From: Risk factors for the development of nosocomial pneumonia and mortality on intensive care units: application of competing risks models

 

Possible endpoints (competing risks)

Risk factor

      
 

Nosocomial pneumonia

Discharge (dead or alive)

 

CSHR

95% CI

p Value

CSHR

95% CI

p Value

Baseline:

Age (continuous variable)

1.01

1.00 to 1.02

0.18

1.00

1.00 to 1.01

0.01

Female gender

0.75

0.53 to 1.07

0.12

1.10

0.99 to 1.22

0.07

SAPS II (continuous variable)

1.00

0.98 to 1.01

0.42

0.98

0.98 to 0.99

< 0.01

Intubation on admission

0.89

0.71 to 1.13

0.35

1.05

0.96 to 1.14

0.32

Pneumonia on admission

0.02

0.00 to 0.12

< 0.01

0.66

0.56 to 0.77

< 0.01

Urinary tract infection on admission

1.86

0.60 to 5.82

0.28

0.81

0.56 to 1.18

0.28

Other infections on admission

1.08

0.59 to 1.98

0.79

0.72

0.59 to 0.89

< 0.01

Hospitalization before admission

0.73

0.50 to 1.05

0.09

0.91

0.81 to 1.02

0.10

Surgical patients

0.69

0.41 to 1.18

0.18

0.98

0.83 to 1.16

0.80

Elective surgery before admission

1.95

1.33 to 2.85

< 0.01

0.54

0.48 to 0.60

< 0.01

Emergency surgery before admission

1.59

1.10 to 2.28

0.01

1.08

0.95 to 1.23

0.25

Cardial/pulmonary underlying disease

1.32

0.86 to 2.04

0.20

0.84

0.73 to 0.97

0.02

Neurological underlying disease

1.25

0.78 to 2.00

0.36

0.94

0.81 to 1.09

0.41

Metabolic/renal underlying disease

0.76

0.35 to 1.65

0.48

0.80

0.65 to 0.99

0.04

Other underlying disease

1.49

0.83 to 2.66

0.18

1.00

0.81 to 1.24

1.00

Time-dependent:

Ventilation

5.90

2.47 to 14.09

< 0.01

0.53

0.45 to 0.62

< 0.01

Chest drainage

1.00

0.68 to 1.46

0.99

0.75

0.65 to 0.86

< 0.01

Colostomy

4.29

0.36 to 50.64

0.25

0.69

0.28 to 1.72

0.42

Enterostomy

0.14

0.01 to 2.10

0.15

1.64

0.61 to 4.45

0.33

Jejunostomy

2.47

0.45 to 13.58

0.30

0.41

0.16 to 1.04

0.06

Nasogastric tube

3.04

1.25 to 7.37

0.01

0.89

0.76 to 1.03

0.12

Urinary catheter

1.53

0.49 to 4.81

0.46

0.76

0.65 to 0.90

< 0.01

  1. CSHR, cause-specific hazard ratio; SAPS, simplified acute physiology score.