|
Time
|
Start of experiment
|
End of experiment
|
|---|
|
Mean BP (mmHg)
| | |
|
LVT-30
|
103.8 ± 1.4
|
87.6 ± 4.0
|
|
LVT-60
|
105.3 ± 2.3
|
75.3 ± 5.2‡
|
|
HVT-30
|
103.8 ± 1.4
|
93 ± 5.1
|
|
HVT-60
|
105.3 ± 1
|
88 ± 4.6
|
|
HVT+dopamine-30
|
106.3 ± 1.7
|
92.3 ± 2.8
|
|
HVT+dopamine-60
|
106.5 ± 2.5
|
97.5 ± 3.8†
|
|
AWP (mmHg)
| | |
|
LVT-30
|
14.8 ± 1.1*
|
16.6 ± 1.1*
|
|
LVT-60
|
13.9 ± 1.2*
|
18.3 ± 0.8*
|
|
HVT-30
|
30 ± 1.7
|
28.8 ± 1.4
|
|
HVT-60
|
31 ± 1.8
|
28 ± 1.6
|
|
HVT+dopamine-30
|
24.6 ± 0.6
|
23 ± 0.9+
|
|
HVT+dopamine-60
|
27.5 ± 1.9
|
26.5 ± 1.3
|
- Ten animals were included in each group. Values are expressed as means ± standard error of the mean. *Statistically significant difference for the comparison of the LVT-30 group with HVT-30 and HVT+DA-30 groups, and of the LVT-60 group with HVT-60 and HVT+DA-60 groups (P = 0.001) at the beginning and end of the experiment. +Statistically significant difference between HVT-30 and HVT+DA-30 groups (P = 0.012) at the end of the experiment. †Statistically significant difference between LVT-60 and HVT+DA-60 groups (P = 0.018) at the end of the experiment. ‡Statistically significant difference between LVT-30 and LVT-60 groups (P = 0.025) at the end of experiment. AWP, airway pressure; BP, blood pressure; HVT-30, high tidal volume for 30 minutes; HVT-60, high tidal volume for 60 minutes; HVT+dopamine-30, high tidal volume plus dopamine for 30 minutes; HVT+dopamine-60, high tidal volume plus dopamine for 60 minutes; LVT-30, low tidal volume for 30 minutes; LVT-60, low tidal volume for 60 minutes.
