Time | Start of experiment | End of experiment |
---|
Mean BP (mmHg) | | |
LVT-30 | 103.8 ± 1.4 | 87.6 ± 4.0 |
LVT-60 | 105.3 ± 2.3 | 75.3 ± 5.2‡ |
HVT-30 | 103.8 ± 1.4 | 93 ± 5.1 |
HVT-60 | 105.3 ± 1 | 88 ± 4.6 |
HVT+dopamine-30 | 106.3 ± 1.7 | 92.3 ± 2.8 |
HVT+dopamine-60 | 106.5 ± 2.5 | 97.5 ± 3.8† |
AWP (mmHg) | | |
LVT-30 | 14.8 ± 1.1* | 16.6 ± 1.1* |
LVT-60 | 13.9 ± 1.2* | 18.3 ± 0.8* |
HVT-30 | 30 ± 1.7 | 28.8 ± 1.4 |
HVT-60 | 31 ± 1.8 | 28 ± 1.6 |
HVT+dopamine-30 | 24.6 ± 0.6 | 23 ± 0.9+ |
HVT+dopamine-60 | 27.5 ± 1.9 | 26.5 ± 1.3 |
- Ten animals were included in each group. Values are expressed as means ± standard error of the mean. *Statistically significant difference for the comparison of the LVT-30 group with HVT-30 and HVT+DA-30 groups, and of the LVT-60 group with HVT-60 and HVT+DA-60 groups (P = 0.001) at the beginning and end of the experiment. +Statistically significant difference between HVT-30 and HVT+DA-30 groups (P = 0.012) at the end of the experiment. †Statistically significant difference between LVT-60 and HVT+DA-60 groups (P = 0.018) at the end of the experiment. ‡Statistically significant difference between LVT-30 and LVT-60 groups (P = 0.025) at the end of experiment. AWP, airway pressure; BP, blood pressure; HVT-30, high tidal volume for 30 minutes; HVT-60, high tidal volume for 60 minutes; HVT+dopamine-30, high tidal volume plus dopamine for 30 minutes; HVT+dopamine-60, high tidal volume plus dopamine for 60 minutes; LVT-30, low tidal volume for 30 minutes; LVT-60, low tidal volume for 60 minutes.