Skip to main content

Table 2 Emergence of imipenem resistance during treatment of Pseudomonas pneumonia

From: The role of carbapenems in initial therapy for serious Gram-negative infections

Authors (year) [ref.] Daily dose (g) Treatment-emergent resistance (n/total [%])
Salata et al. (1985) [36] 1.5 to 3 6/10 (60)
Quinn et al. (1986) [38]   
Norrby et al. (1993) [35] 2 6/19 (32)
Cometta et al. (1994) [32] 2a 14/21 (67)
Fink et al. (1994) [33] 3 17/32 (53)
Jaccard et al. (1998) [34] 2 6/24 (25)
Zanetti et al. (2003) [37] 2 9/27 (33)
  1. aSome patients also received 150 mg netilmicin twice a day.