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Table 1 Effect of extended infusion of carbapenem antibiotics

From: Pharmacodynamic optimization of β-lactams in the patient care setting

  Bactericidal cumulative reaction of response (%)a  
Antibiotic regimen 30-minute infusion 3-hour infusion Change (%)
Imipenem 1 g q8h 69.3 72.0 +2.7
Meropenem 1 g q8h 77.1 83.8 +6.7
Meropenem 2 g q8h 84.1 88.1 +4.0
  1. Shown is the effect of extended infusion of carbapenem antibiotics on the bactericidal cumulative fraction of response against multidrug-resistant Pseudomonas aeruginosa [17]. aBactericidal exposure defined as 40% time above minimum inhibitory concentration. q8h, every 8 hours.