Table 1 Baseline Clinical Characteristics and Laboratory Values of Subjects
From: Cardiovascular response to dobutamine stress predicts outcome in severe sepsis and septic shock
| Â | All (n = 23) | Non-survivors (n = 15) | Survivors (n = 8) | P value |
|---|---|---|---|---|
Male/female | 11 M; 12 F | 7 M; 8 F | 4 M; 4 F | NS |
Age | 62.6 ± 4.0 | 61.4 + 5.5 | 64.8 ± 5.6 | NS |
Mechanical ventilation | 17/23 | 13/15 | 4/8 | NS |
PO2/FiO2 | 171.8 ± 20.8 | 147.2 ± 21.1 | 217.9 ± 42.4 | NS |
Pressor use | 20/23 | 13/15 | 7/8 | NS |
Dopamine dose (μg/kg/min) | 6.8 ± 1.6 | 7.6 ± 2.5 | 5.9 + 1.8 | NS |
Norepinephrine dose (μg/kg/min) | 0.22 ± 0.05 | 0.17 ± 0.05 | 0.30 ± 0.10 | NS |
Number of organ failures | 5.3 ± 0.3 | 5.9 ± 0.3 | 4.3 ± 0.5 | 0.0138 |
APACHE II | 27.3 ± 1.5 | 28.9 ± 1.8 | 24.4 ± 2.6 | NS |
SAPS | 55.2 ± 2.8 | 61.5 ± 11.3 | 43.4 ± 2.7 | 0.0002 |
Serum creatinine (mg/dL) | 2.4 ± 0.3 | 2.4 ± 0.4 | 2.4 ± 0.5 | NS |
Serum albumin (g/dL) | 2.3 ± 0.1 | 2.2 ± 0.1 | 2.7 ± 0.2 | 0.0498 |
Serum bilirubin (mg/dL) | 3.2 ± 1.2 | 4.5 ± 1.7 | 0.7 ± 0.1 | 0.0444 |
Platelets (× 103 per uL) | 171 ± 32 | 119 ± 31 | 269 ± 60 | 0.0483 |
PT | 15.9 ± 0.7 | 17.1 ± 0.9 | 13.8 ± 0.7 | 0.0069 |
Serum lactate (mmol/L) | 2.7 ± 0.3 | 2.9 ± 0.5 | 2.5 ± 0.5 | NS |
Bacteraemia | 10/23 | 7/15 | 3/8 | NS |
Organisms | 4 S. aureus 3 E.coli 1 S. pneumoniae 1 P. mirabilis 1 C. albicans | 4 S. aureus 1 E. coli 1 P. mirabilis 1 C. albicans | 2 E. coli 1 S. pneumoniae | Â |
Underlying disorder | 5 post-op 4 cancer 2 diabetes 1 each pancreatitis, sickle cell crisis, AIDS, CVA, trauma, cirrhosis, dementia, epilepsy 4 nil | 4 post-op 4 cancer 1 each pancreatitis, sickle cell crisis, AIDS, CVA, trauma, cirrhosis, nil | 3 nil 2 diabetes 1 each post-op, dementia, epilepsy | Â |
Clinical infection | 13 pneu 5 bsi 2 uti 2 peritonitis 1 ssti | 7 pneu 5 bsi 1 uti, ssti, peritonitis | 6 pneu 1 uti 1 peritonitis | Â |