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Table 4 Multivariable regression analysis (maximum likelihood estimation): intensive care unit and hospital mortalitya

From: Intensive insulin therapy and mortality in critically ill patients

  Period II
(n = 3,322)b
1 Mar 02 to 30 Jun 03
Period III
(n = 4,786)b
1 Jul 03 to 28 Feb 05
  OR (95% CI) P value OR (95% CI) P value
Entire ICU population
  n = 3,310   n = 4,739  
ICU mortality 1.20 (0.98, 1.47) 0.071 1.26 (1.04, 1.53) 0.019
Hospital mortality 1.11 (0.93, 1.31) 0.248 1.15 (0.98, 1.35) 0.088
Entire ICU population, ICU LOS ≤ 3 days
  n = 1,808   n = 2,619  
ICU mortality 1.21 (0.84, 1.74) 0.317 1.65 (1.16, 2.33) 0.005
Hospital mortality 1.17 (0.87, 1.57) 0.288 1.47 (1.11, 1.93) 0.007
Entire ICU population, ICU LOS >3 days
  n = 1,484   n = 2,033  
ICU mortality 1.21 (0.95, 1.54) 0.125 1.14 (0.90, 1.44) 0.268
Hospital mortality 1.08 (0.87, 1.33) 0.501 1.01 (0.83, 1.24) 0.918
  1. aAll estimates are adjusted for admission age, history of diabetes, Simplified Acute Physiology Score (SAPS) II with age points removed, mechanical ventilation at ICU admission, and admitting service. bPeriod I is used as reference category for all analyses (n = 2,366 for the entire ICU population, n = 1,282 for patients in ICU ≤3 days, and n = 1,067 for patients in ICU >3 days). CI, confidence interval; ICU, intensive care unit; LOS, length of stay; OR, odds ratio.
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