Critical care management and outcome of severe Pneumocystis pneumonia in patients with and without HIV infection

Table 1 Main characteristics of the patients at admission

	HIV-negative cases	HIV-positive cases
	n = 27	n = 46
Gender, male/female	11/16	34/12^a
Age, years	64 (18–82)	37 (23–56)^a
Duration of symptoms before ICU, days	10 (4–45)	18 (4–90)^a
Simplified Acute Physiology Score II	38 (13–90)	27 (11–112)^a
Respiratory rate, breaths per minute	32 (16–41)	32 (20–48)
PaO₂/FiO₂ ratio, mm Hg	160 (61–322)	183 (38–380)
PaCO₂, mm Hg	34 (26–49)	35 (16–60)
Circulatory failure, number	7 (26)	7 (15)
Blood lactate, mmol/L	1.8 (0.6–16.4)	1.4 (0.2–15)

Values are expressed as median (range) or as absolute value (percentage). ^aP < 0.05 versus HIV-negative cases. ICU, intensive care unit; PaCO₂, arterial partial pressure of carbon dioxide; PaO₂/FiO₂, arterial partial pressure of oxygen/fraction of inspired oxygen.

ISSN: 1364-8535