Table 2 Neutrophil and monocyte ROS generation in septic patients (n = 41) and controls (n = 17) constitutively and after PMA, fMLP, LPS and S. aureus stimulation. Values are expressed in median and ranges of GMFI. p < 0.01 comparing patients and controls in all tested conditions.
| Â | Neutrophil | Monocyte | ||
|---|---|---|---|---|
| Â | Patients | Controls | Patients | Controls |
Baseline | 55.9 (17 to 167.9) | 14.9 (8 to 77) | 32.6 (11.7 to 130.5) | 8.3 (3.7 to 32.1) |
PMA | 59.6 (31.7 to 1,630.1) | 28.5 (11.2 to 487.4) | 44.3 (3.4 to 375.9) | 14.5 (5.7 to 63) |
fMLP | 102.6 (19.5 to 584.3) | 10.5 (1.8 to 142) | 15.6 (1.3 to 183.4) | 5.4 (1.5 to 51.9) |
LPS | 103.9 (46.2 to 343.5) | 18.6 (1.8 to 63.3) | 41.2 (1.5 to 116.6) | 8.6 (1.4 to 25) |
S. aureus | 419.2 (93.3 to 1,356.2) | 48.1 (24.9 to 155) | 79.4 (26.4 to 322.9) | 15.4 (9.7 to 31.4) |