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Figure 1 | Critical Care

Figure 1

From: Expression of cell surface receptors and oxidative metabolism modulation in the clinical continuum of sepsis

Figure 1

Analysis of the expression of surface receptors on neutrophils in whole blood in healthy volunteers (n = 17), patients with sepsis (n = 14), severe sepsis (n = 12) and septic shock (n = 15). Neutrophils were gated based on FSC versus SSC (forward scatter and side scatter) parameters and CD66b+ CD14- stained cells. Surface markers were analyzed in histograms and expressed as the geometric mean fluorescence intensity (GMFI): Toll-like receptor (TLR)2 (A), TLR4 (B), CD11b (C), CD11c (D) and CD66b (E). Values represented are median, range, and quartiles 25–75%. 'o' represents outliers; *p < 0.05 compared to the other groups; #p < 0.05 compared to healthy volunteers (Kruskal-Wallis followed by Mann-Whitney test).

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