Alveolar recruitment can be predicted from airway pressure-lung volume loops: an experimental study in a porcine acute lung injury model

Table 1 Lung mechanics and blood gas tensions obtained at 10 cmH₂O before and after LRM

Parameter	Before lung lavage		After lung lavage		After lung lavage and additional injurious ventilation
	Before LRM	After LRM	Before LRM	After LRM	Before LRM	After LRM
EELV, l	0.68 (0.61, 0.71)	0.83^a (0.77, 0.86)	0.37^b (0.31, 0.46)	0.69^a (0.62, 0.78)	0.42^b (0.40, 0.46)	0.73^a (0.65, 0.78)
Crs, ml/cmH₂O	9.5 (9.3, 10.1)	11.5^a (11.0, 12.0)	5.8^b (5.2, 6.6)	10.2^a (9.8, 11.0)	6.6^b (5.8, 7.0)	10.5^a (10.1, 10.8)
PaO₂, kPa	71.2 (66.6, 80.0)	80.1^a (68.4, 82.3)	51.0^b (41.4, 56.4)	69.9^a (66.5, 77.7)	32.4^b (16.1, 45.6)	71.9^a (66.4, 76.2)
PaCO₂, kPa	4.5 (4.3, 4.6)	4.4 (3.8, 5.0)	7.8^b (7.2, 9.7)	5.9^a (5.3, 7.2)	6.8^b (6.3, 7.4)	5.5^a (4.8, 6.3)

LRM, lung recruitment maneuver; PEEP, positive end-expiratory pressure; EELV, end-expiratory lung volume; Crs, compliance of the respiratory system; PaCO₂, partial pressure of arterial CO₂; PaO₂, partial pressure of arterial oxygen.
The three lung conditions: before lung lavage, after lung lavage and after lung lavage and additional injurious mechanical ventilation
Results are presented as medians and 25th and 75th centiles.
^aP < 0.05, before LRM compared with after LRM in the three lung conditions; ^bP < 0.05, before lung lavage compared with after lung lavage or after lung lavage and additional injurious ventilation before the LRM.

ISSN: 1364-8535