Table 1 Demographic characteristics of severe sepsis patients with and without invasive fungal infection

   Age (years)

65 (50–76.25)

61.5 (45–73)

NS

   Sex (male; n [%])

57 (63.3%)

149 (65.4%)

NS

   Admission APACHE II score (mean [IQR])

21 (17–27)

18 (13–23)

0.001

   Admission SOFA score(mean [IQR])

8 (6–12)

8 (5–11.75)

NS

   Comorbidity (n [%])

71 (78.9%)

165 (72.4%)

NS

   Cancer (n [%])

14 (15.6%)

24 (10.5%)

NS

   Diabetes mellitus (n [%])

15 (16.7%)

26 (11.4%)

NS

Interventions

   Mechanical ventilation (n [%])

71 (78.9%)

75 (32.9%)

<0.001

   Central venous catheterization (n [%])

74 (82.2%)

122 (53.5%)

<0.001

   Urinary catheterization (n [%])

84 (93.3%)

137 (60.1%)

<0.001

   Arterial catheterization (n [%])

51 (56.7%)

112 (49.1%)

NS

   Total parenteral nutrition (n [%])

49 (54.4%)

99 (43.4%)

NS

Corticosteroids or immunodepressant drugs (n [%])

22 (24.4%)

45 (19.7%)

NS

Renal replacement therapy (n [%])

21 (23.3%)

28 (12.3%)

0.024

Outcomes

   ICU LOS (days; mean [IQR])

16 (7.75–31)

5 (2–10)

<0.001

   Hospital LOS (days; mean [IQR])

29.5 (17.75–50.25)

19 (10.25–36)

<0.001

   Daily costs ($; mean ± SD)

520 ± 319

481 ± 437

NS

   Hospital costs ($; mean ± SD)

17,051 ± 14,183

8,474 ± 9,484

0.001

   Hospital mortality

61 (67.8%)

94 (41.2%)

<0.001