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Table 5 Time course of haemodynamic parameters and parameters of kidney function

From: Effects of plasma expansion with albumin and paracentesis on haemodynamics and kidney function in critically ill cirrhotic patients with tense ascites and hepatorenal syndrome: a prospective uncontrolled trial

Parameter

Before paracentesis

After paracentesis

  

12 h

24 h

36 h

48 h

MAP (mmHg)

81 (74–100)

80 (69–92)

77 (68–93)

74 (64–92)a

84 (75–96)

CVP (mmHg)

11 (7–14)

7 (4–11)

9 (7–13)

7 (5–13)

9 (7–12)

GEDVI (ml m-2)

776 (717–917)

750 (683–900)

810 (693–952)

838 (650–946)

798 (668–882)

SVRI (dyn s cm-5 m-2)

1,639 (1,168–2,037)

1,552 (1,105–1,809)

1,487 (1,205–1,808)

1,381 (1,044–2,023)

1,591 (1,160–2,088)

CI (l min-1 m-2)

4.1 (3.2–4.3)

3.9 (3.3–4.5)

4.1 (3.5–4.7)

3.8 (3.4–4.5)

3.9 (3.5–4.4)

CC (ml min-1)

23 (12–49)

33 (16–50)a

34 (17–66)a

33 (16–60)a

44 (18–72)a

FeNa %

0.035 (0.020–0.063)

0.055 (0.038–0.120)a

0.060 (0.040–0.118)a

0.040 (0.020–0.080)

0.040 (0.020–0.060)

  1. Data are presented as median (25th to 75th centile). MAP, mean arterial pressure; CVP, central venous pressure; GEDVI, global end-diastolic volume index; SVRI, systemic vascular resistance index; CI, cardiac index; CC, creatinine clearance; FeNa, fractional excretion of sodium. aP < 0.05 compared with baseline. Adjustment for multiple testing according to Bonferroni.