Period | Direction of BNP change | n (ΔBNP, pg/ml) |
P
|
---|
| | ALI/ARDS | CHF | |
---|
Days 1 to 2 | Increase | 17 (254 ± 302) | 5 (228 ± 287) | |
| Decrease | 9 (-246 ± 178) | 8 (-252 ± 208) | 0.17b |
| Alla | 26 (73 ± 339) | 17 (-52 ± 290) | 0.21c |
Days 2 to 3 | Increase | 9 (143 ± 200) | 5 (396 ± 132) | |
| Decrease | 11 (-191 ± 187) | 7 (-160 ± 142) | 1.0b |
| Alla | 24 (-34 ± 231) | 15 (57 ± 281) | 0.28c |
- BNP, B-type natriuretic peptide; ALI, acute lung injury; ARDS, acute respiratory distress syndrome; CHF, congestive heart failure. The table shows an analysis of changes in BNP levels in direction (increase or decrease) and magnitude (ΔBNP) from day 1 to day 2 and from day 2 to day 3, classified by edema type. Where errors are shown, results are means ± SD.
- aValues for some patients remained above the upper limit of the assay (1,300 pg/ml) and were consider unchanged. bχ2 comparing the proportion of subjects with an increase in BNP by edema type; ct test of magnitude of BNP change by edema type.