Time-dependency of improvements in arterial oxygenation during partial liquid ventilation in experimental acute respiratory distress syndrome

Table 2 Gas exchange, peak airway pressure and metabolic data

			PLV with 7.5 ml/kg FC 3280		PLV with 15 ml/kg FC 3280		PLV with 22.5 ml/kg FC 3280		PLV with 30 ml/kg FC 3280
	Baseline	Ali	5 min	30 min	5 min	30 min	5 min	30 min	5 min	30 min
AvDO₂ (ml/100 ml)	3.4 ± 0.9	2.8 ± 0.6	2.9 ± 0.4	2.6 ± 0.5	3.2 ± 0.4	3.1 ± 0.6	3.1 ± 0.5	2.9 ± 0.7	3.4 ± 0.6	3.1 ± 0.7
VO₂ (ml/min)	158 ± 41	157 ± 44	163 ± 24	139 ± 31	159 ± 23	160 ± 37	146 ± 20	146 ± 36	164 ± 39	162 ± 48
DO₂ (ml/min)	549 ± 189	345 ± 160	391 ± 111	351 ± 109	444 ± 138	420 ± 139	452 ± 135	441 ± 121	461 ± 104^*	455 ± 122^*
PaCO₂ (mmHg)	39 ± 7	48 ± 6	48 ± 5	49 ± 4	49 ± 4	49 ± 8	47 ± 4	49 ± 5	49 ± 3	49 ± 3
pH	7.48 ± 0.08	7.37 ± 0.06	7.38 ± 0.05	7.36 ± 0.04	7.36 ± 0.04	7.35 ± 0.04	7.37 ± 0.05	7.38 ± 0.04	7.37 ± 0.03	7.38 ± 0.05
Peak airway pressure (cmH₂O)	16 ± 3	31 ± 5	26 ± 2^*	29 ± 6	27 ± 5^*	29 ± 6	29 ± 7	29 ± 7	31 ± 6	31 ± 8

Values are expressed as mean ± standard deviation.^*P < 0.05 versus acute lung injury (ALI).avDO₂, arteriovenous oxygen content difference; DO₂,oxygen delivery; VO₂, oxygen consumption;PaCO₂, arterial carbon dioxide tension; PLV, partial liquidventilation.

ISSN: 1364-8535