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Table 1 Conventional ventilation versus APRV

From: Airway pressure release ventilation: an alternative ventilation mode for pediatric acute respiratory distress syndrome

  APRV time (hours)
  Pre-enrollment to APRV T1 T24 T48 T72
PIP/Phigh (cmH2O) 36.6 ± 11.5 33.3 ± 5.7 30.3 ± 5.5 29 ± 1.4 25.5 ± 2.1
MAP (cmH2O) 17.9 ± 5.9 27 ± 2.64 24.6 ± 4.16 23.5 ± 0.7 21.6 ± 2.3
PEEP/Plow (cmH2O) 13.3 ± 1.5 0 0 0 0
Thigh (sec)   3.6 ± 0.5 3.7 ± 0.4 3.8 ± 0.2 3.65 ± 0.21
Tlow (sec)   0.73 ± 0.2 0.76 ± 0.11 0.9 ± 0 0.75 ± 0.21
VTe (mL/kg) 8.3 ± 1.5 13.2 ± 1.1 12 ± 1.7 11.0 ± 1.41 9.5 ± 6.7
Set FiO2 (%) 96.6 ± 2.3 68.3 ± 11.5 60.0 ± 5 57.5 ± 3.5 52.5 ± 3.5
   T4 T24 T48 T72
pH 7.23 ± 9.7 7.32 ± 9.5 7.35 ± 6.42 7.34 ± 4.9 7.39 ± 1.41
pCO2, mmHg 72.3 ± 21.4 63.4 ± 16.8 61.4 ± 7.85 56.4 ± 6.43 57.0 ± 12.7
  1. PIP, peak airway pressure; MAP, mean alveolar pressure; PEEP, positive end expiratory pressure; VTe, expiratory tidal volume; FiO2, fractional oxygen concentration; T, time