Figure 2 From: Determinants of blood pH in health and disease Plot of pH versus strong ion difference (SID). For this plot,total weak acid concentration (ATOT) and partial carbon dioxidetension (pCO2) were held constant at 18 mmol/l and 40 mmHg,respectively. Assumes a water dissociation constant for blood of 4.4 ×10–14 (mol/l). Note how steep the pH curve becomes at SID <20 mmol/l.Adapted from Kellum and Kellum [10].Back to article page