Predictors of outcome in myxoedema coma: a study from a tertiary care centre

Table 2 Factors predicting mortality in survivors and non-survivors

	Survivors (n = 11)	Non-survivors (n = 12)	P value
Age, years	57.36 ± 12.55	61.50 ± 16.97	0.517
Lag time, days	10.64 ± 6.39	10.33 ± 12.29	0.942
Stoppage of L-thyroxine	4	10	0.036^a
Use of sedatives	7	12	0.037^a
Heart rate, beats per minute	77.45 ± 14.45	61.25 ± 18.13	0.028^a
Mean blood pressure, mm Hg	117.64 ± 24.88	90.45 ± 32.28	0.039^a
Thyroxine, nmol/L	19.84 ± 19.45	23.42 ± 14.46	0.616
Thyroid-stimulating hormone, mU/L	56.99 ± 39.40	57.87 ± 51.99	0.964
Glucocorticoid deficiency	2	5	0.371
Sepsis	6	1	0.027^a
Unresponsive hypothermia	5	10	0.027^a
Mechanical ventilation	2	10	0.003^a
Intravenous thyroxine	2	3	0.9
Glasgow Coma Scale	8.55 ± 3.39	5.50 ± 2.47	0.022^a
APACHE II score	12.09 ± 4.95	18.08 ± 8.02	0.045^a
SOFA score, baseline	8.5 ± 3.1	6.6 ± 3.9	0.22
SOFA score, minimum	1.45 ± 1.04	7.58 ± 3.00	0.000^a
SOFA score, maximum	7.36 ± 3.38	15.17 ± 1.99	0.000^a
Hospital stay, days	20.73 ± 24.67	11.42 ± 11.09	0.249

APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sequential Organ Failure Assessment.

ISSN: 1364-8535