Skip to main content

Table 3 Regional blood flow and oxygen delivery during infusion of vasopressin in non-septic animals

From: Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow

Time   300 minutes 360 minutes 480 minutes
Portal vein (mL/kg per minute)a,b     
  Group C 33 ± 3 32 ± 5 30 ± 4
  Group V 33 ± 8 23 ± 4c 25 ± 4c
Hepatic artery (mL/kg per minute)a     
  Group C 3.2 ± 1.7 3.4 ± 1.7 3.7 ± 1.7
  Group V 4.4 ± 1.6 8.2 ± 3.1c 8 ± 2.5c
MBF liver (percentage)     
  Group C 133 ± 53 135 ± 61 122 ± 57
  Group V 85 ± 22 75 ± 38 77 ± 44
MBF kidney (percentage)a     
  Group C 96 ± 14 94 ± 20 96 ± 20
  Group V 106 ± 15 86 ± 16c 105 ± 15
MBF pancreas (percentage)a     
  Group C 119 ± 14 108 ± 18c 99 ± 17c
  Group V 110 ± 30 74 ± 15c 76 ± 23c
  1. A continuous infusion of vasopressin (0.06 IU/kg per hour) was started at t = 300 minutes in group V. Animals in group C received intravenous saline only.
  2. ap < 0.01 time-group interaction groups V versus C: effect of vasopressin in control animals.
  3. bp < 0.05 Mann-Whitney test (area under curve): effect of vasopressin in non-septic versus septic animals.
  4. cp < 0.01 compared to t = 300 minutes.
  5. Group C: non-septic control group. Group V: non-septic vasopressin control group. Hepatic artery: blood flow in the hepatic artery. MBF kidney: microcirculatory blood flow in the renal cortex. MBF pancreas: microcirculatory blood flow in the pancreas. MBF was measured by laser Doppler flowmetry and expressed as percentage of baseline. Portal vein: blood flow in the portal vein.