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Table 4 Variables of cerebral circulation and oxygenation before and after reduction of the arterial carbon dioxide partial pressure (PaCO2) by 0.93 kPa

From: Cerebral haemodynamics and carbon dioxide reactivity during sepsis syndrome

  Baseline Decreased PaCO2
Cerebral blood flow (ml/100 g/min) 64 ± 29 39 ± 15**
Blood flow velocity in the middle cerebral artery (cm/s) 72 ± 25 59 ± 22**
Cerebral critical closing pressure (mmHg) 25 ± 11 39 ± 15**
Physiological effective cerebral perfusion pressurea (mmHg) 65 ± 16 48 ± 17**
Cerebral metabolic rate of oxygen (ml/100 g/min) 1.9 ± 0.8 1.9 ± 0.9
Venous oxygen saturation in the jugular bulb (%) 75 ± 8 67 ± 14*
  1. aMean arterial pressure minus cerebral critical closing pressure. *P < 0.01 and **P < 0.001, matched pairs t test, n = 10.