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Figure 3 | Critical Care

Figure 3

From: Platelet-derived exosomes from septic shock patients induce myocardial dysfunction

Figure 3

Effect of reactive oxygen species (ROS) inhibitors on exosome-induced inhibition of left ventricular pressure. Effect of ROS inhibitors on exosome-induced inhibition of maximal positive (a) and negative (b) derivatives of ventricular pressure. Data are mean ± standard error of the mean of nine experiments for exosomes from septic patients, four experiments for septic exosomes + L-monomethyl-arginine (LNMMA), five experiments for septic exosomes + n-acetylcysteine (NAC), four experiments for septic exosomes + dyphenyleneiodonium (DPI), three experiments for septic exosomes + apocynin (APO), and three experiments for septic exosomes + indomethacin (INDO). *p < 0.05 versus septic; (analysis of variance two-way, Tukey test). +dP/dtmax, maximal positive derivative of left ventricular pressure; -dP/dtmax, maximal negative derivative of left ventricular pressure.

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