Figure 2
From: Platelet-derived exosomes from septic shock patients induce myocardial dysfunction
Effect of exosomes on left ventricular pressure in isolated rabbit heart preparations. Time course of positive (a) and negative (b) derivatives of left ventricular pressure after infusion of exosomes from septic patients and healthy volunteers. Data are mean ± standard error of the mean of nine experiments for exosomes derived from septic patients and five experiments for exosomes from healthy individuals. *p < 0.05 versus baseline; #p < 0.05 versus 20 minutes (analysis of variance two-way, Tukey test). +dP/dtmax, maximal positive derivative of left ventricular pressure; -dP/dtmax, maximal negative derivative of left ventricular pressure.