Table 4 Frequency of outcome death depending on patient characteristics and extrinsic risk factors

Age ≥ median (64 years)

27 (51.9)

25 (48.1)

8 (29.6)

7 (28.0)

1.00

0.95

Gender, male

15 (28.8)

37 (71.2)

4 (26.7)

11 (29.7)

1.00

1.12

Simplified Acute Physiology Score > median (31)

27 (51.9)

25 (48.1)

6 (22.2)

9 (36.0)

0.36

1.62

Time at risk on SICU > median (8.5 days)

26 (50.0)

26 (50.0)

5 (19.2)

10 (38.5)

0.22

2.00

Ventilation time > median (4.7 days)

26 (50.0)

26 (50.0)

2 (7.7)

13 (50.0)

0.002

6.50

Bronchoscopy

24 (46.1)

28 (53.9)

3 (12.5)

12 (42.9)

0.03

3.43

Number of bronchoscopies > median (1)

37 (71.1)

15 (28.9)

10 (27.0)

5 (33.3)

0.74

1.23

Tracheotomy

46 (88.5)

6 (11.5)

11 (23.9)

4 (66.7)

0.05

2.79

Reintubation

37 (71.1)

15 (28.9)

10 (27.0)

5 (33.3)

0.74

1.23

Reanimation

44 (84.6)

8 (15.4)

12 (27.3)

3 (37.5)

0.68

1.38

Cardiovascular disease

   Cardiomyopathy^b

48 (92.3)

4 (7.7)

15 (31.3)

0 (0)

0.31

-

   Valvular heart disease

35 (67.3)

17 (32.7)

11 (31.4)

4 (23.5)

0.75

0.75

   Cystic fibrosis^b

51 (98.1)

1 (1.9)

15 (29.4)

0 (0)

1.00

-

   Infrarenal aortic aneurysm

47 (90.4)

5 (9.6)

13 (27.7)

2 (40.0)

0.62

1.45

   Suprararenal aortic aneurysm

47 (90.4)

5 (9.6)

14 (29.8)

1 (20.0)

1.00

0.67

   Coronary heart disease

37 (71.1)

15 (28.9)

8 (21.6)

7 (46.7)

0.10

2.16

   Congenital valvular heart disease

48 (92.3)

4 (7.7)

14 (29.2)

1 (25.0)

1.00

0.86

Surgical intervention

   Solid organ transplantation

44 (84.6)

8 (15.4)

14 (31.8)

1 (12.5)

0.41

0.39

   Left ventricular assist device

43 (82.7)

9 (17.3)

12 (27.9)

3 (33.3)

0.71

1.19

   Coronary artery bypass graft

38 (73.1)

14 (26.9)

9 (23.7)

6 (42.9)

0.19

1.81

   Aortic surgery

41 (78.8)

11 (21.2)

12 (29.3)

3 (27.3)

1.00

0.93

   Valve surgery

37 (71.1)

15 (28.9)

12 (32.4)

3 (20.0)

0.51

0.62

Immunosuppression

27 (51.9)

25 (48.1)

9 (33.3)

6 (24.0)

0.55

0.72

   Steroids

28 (53.8)

24 (46.2)

10 (35.7)

5 (20.8)

0.36

0.58

   Cyclosporin

46 (88.5)

6 (11.5)

14 (30.4)

1 (16.7)

0.66

0.55

   Mycophenolate mofetil

44 (84.6)

8 (15.4)

14 (31.8)

1 (12.5)

0.41

0.39

   Basiliximab

46 (88.5)

6 (11.5)

14 (30.4)

1 (16.7)

0.66

0.55

   Tacrolimus

48 (92.3)

4 (7.7)

14 (29.2)

1 (25.0)

1.00

0.86

Blood products^b

2 (3.8)

50 (96.2)

0 (0)

15 (30.0)

1.00

-

   Erythrocyte concentrates

8 (15.4)

44 (84.6)

1 (12.5)

14 (31.8)

0.41

2.55

   Fresh frozen plasma^b

4 (7.7)

48 (92.3)

0 (0)

15 (31.3)

0.31

-

   Thrombocyte concentrates

15 (28.8)

37 (71.2)

2 (13.3)

13 (35.1)

0.18

2.64

   Number of erythrocyte concentrates > median (7)

27 (51.9)

25 (48.1)

4 (14.8)

11 (44.0)

0.03

2.97

   Number of fresh frozen plasma units > median (11.5)

26 (50.0)

26 (50.0)

4 (15.4)

11 (42.3)

0.06

2.75

   Number of thrombocyte concentrates > median (3)

26 (50.0)

26 (50.0)

4 (15.4)

11 (42.3)

0.06

2.75

   Clotting factors

31 (59.6)

21 (40.4)

6 (19.4)

9 (42.9)

0.12

2.21

C1 esterase inhibitor

49 (94.2)

3 (5.8)

13 (26.5)

2 (66.7)

0.20

2.51

Herpes simplex virus-related tracheobronchitis or pneumonia^b

45 (86.5)

7 (13.5)

8 (17.8)

7 (100)

<0.0001

-

Pneumonia

46 (88.5)

6 (11.5)

11 (23.9)

4 (66.7)

0.05

2.79