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Table 2 Clinical and virologic characteristics of patients with herpes simplex virus type 1 detection in respiratory specimens

From: Clinical relevance of and risk factors for HSV-related tracheobronchitis or pneumonia: results of an outbreak investigation

Cluster Patient/Isolate

Clinical presentation besides herpes simplex virus-associated presentations

Herpes simplex virus detection

Outcome

  

Specimen type

Direct immunofluorescence testing

Virus culture

PCR

 

C1

Right-sided heart failure

Tracheal aspirate

-

-

+

Death

C2

Infection of the aortic Y-prosthesis, intraabdominal bleedings

Bronchoalveolar lavage

+

+

+

Death

C3

-

Bronchoalveolar lavage

+

-

+

Survival

C4

Adult respiratory distress syndrome, internal carotid artery stenosis

Tracheal aspirate

+

+

+

Death

C5

Adult respiratory distress syndrome

Nasopharyngeal swab

+

+

+

Death

C6

-

Bronchoalveolar lavage

+

+

+

Death

C7

Peritonitis with coagulase-negative Staphylococci

Bronchoalveolar lavage

+

+

+

Death

C8

Sepsis

Bronchoalveolar lavage

+

+

+

Death