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Table 3 Comparison of disease characteristics based on serogroup of Neisseria meningitidis

From: Improved survival of children with sepsis and purpura: effects of age, gender, and era

  N. meningitidis a
  Serogroup B Serogroup C
Total number of children 175 44
Age in years 2.8b 6.0b
  (0.1 to 17.9) (0.1 to 16.5)
PRISM score 16 14
  (1 to 37) (1 to 35)
Predicted death rate (%)c 8.9 4.9
  (0 to 100) (0 to 100)
Number of children with DIC (%) 128 32
  (81) (74)
Number of PICU-free days 24 25
  (0 to 28) (0 to 27)
Base excess (mmol/L) -8 -8.0
  (-21 to 4.4) (-28 to 3)
Lactate (mmol/L) 4.2 3.5
   Geometric mean, 95% CI 3.8 to 4.6 2.9 to 4.2
C-reactive protein (mg/L) 82d 128d
  (6 to 287) (20 to 326)
Fibrinogen (g/L) 2.4 2.8
  (0.2 to 6.8) (0.3 to 6.6)
Platelet count (×103/μL) 110 113
  (15 to 475) (13 to 336)
Leukocytes (×103/μL) 8.8e 12.2e
   Geometric mean, 95% CI 7.6 to 10.1 9.9 to 15.0
Glucose (mmol/L) 5.9 6.2
   Geometric mean, 95% CI 5.4 to 6.5 5.5 to 6.9
  1. aResults represent median (min-max) unless stated otherwise. bp < 0.001. cPredicted death rate was based on the Rotterdam score. dp < 0.01. ep < 0.05. CI, confidence interval; DIC, disseminated intravascular coagulation; PICU, paediatric intensive care unit; PRISM, Paediatric Risk of Mortality.