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Table 1 Comparison of disease characteristics between non-survivors and survivors

From: Improved survival of children with sepsis and purpura: effects of age, gender, and era

  Survivorsa Non-survivorsa
Total number of children (%) 242 45
  (84.3) (15.7)
Male-to-female ratio 1.1 1.7
Number of children with DIC (%) 174b 32b
  (75) (97)
Neisseria meningitidis serogroup   
   B (%) 147 (74.2) 28 (73.7)
   C (%) 37 (18.7) 7 (18.4)
PRISM score 14c 23c
  (1 to 37) (8 to 44)
Predicted death rate (%)d 3.1c 87.4c
  (0 to 100) (1.1 to 100.0)
Base excess (mmol/L) -7c -13c
  (-23 to 4.4) (-28 to 0.6)
Lactate (mmol/L) 3.7c 6.6c
   Geometric mean, 95% CI 3.4 to 4.3 5.8 to 7.4
C-reactive protein (mg/L) 106c 53c
  (10 to 334) (6 to 226)
Fibrinogen (g/L) 2.8c 0.9c
  (0.3 to 6.8) (0.2 to 5.4)
Platelet count (×103/μL) 126c 47c
  (15 to 475) (13 to 202)
Leukocytes (×103/μL) 10.6c 4.7c
   Geometric mean, 95% CI 9.5 to 11.9 3.7 to 6.0
Glucose (mmol/L) 6.3c 4.3c
   Geometric mean, 95% CI 5.9 to 6.8 3.6 to 5.3
  1. aResults represent median (min-max) unless stated otherwise. bp < 0.01.cp < 0.001. dPredicted death rate was based on the Rotterdam score. CI, confidence interval; DIC, disseminated intravascular coagulation; PRISM, Paediatric Risk of Mortality.