Improved survival of children with sepsis and purpura: effects of age, gender, and era

Table 1 Comparison of disease characteristics between non-survivors and survivors

	Survivors^a	Non-survivors^a
Total number of children (%)	242	45
	(84.3)	(15.7)
Male-to-female ratio	1.1	1.7
Number of children with DIC (%)	174^b	32^b
	(75)	(97)
Neisseria meningitidis serogroup
B (%)	147 (74.2)	28 (73.7)
C (%)	37 (18.7)	7 (18.4)
PRISM score	14^c	23^c
	(1 to 37)	(8 to 44)
Predicted death rate (%)^d	3.1^c	87.4^c
	(0 to 100)	(1.1 to 100.0)
Base excess (mmol/L)	-7^c	-13^c
	(-23 to 4.4)	(-28 to 0.6)
Lactate (mmol/L)	3.7^c	6.6^c
Geometric mean, 95% CI	3.4 to 4.3	5.8 to 7.4
C-reactive protein (mg/L)	106^c	53^c
	(10 to 334)	(6 to 226)
Fibrinogen (g/L)	2.8^c	0.9^c
	(0.3 to 6.8)	(0.2 to 5.4)
Platelet count (×10³/μL)	126^c	47^c
	(15 to 475)	(13 to 202)
Leukocytes (×10³/μL)	10.6^c	4.7^c
Geometric mean, 95% CI	9.5 to 11.9	3.7 to 6.0
Glucose (mmol/L)	6.3^c	4.3^c
Geometric mean, 95% CI	5.9 to 6.8	3.6 to 5.3

^aResults represent median (min-max) unless stated otherwise. ^bp < 0.01.^cp < 0.001. ^dPredicted death rate was based on the Rotterdam score. CI, confidence interval; DIC, disseminated intravascular coagulation; PRISM, Paediatric Risk of Mortality.

ISSN: 1364-8535