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Table 3 Renal function and metabolic effects

From: An exploratory study with an adaptive continuous intravenous furosemide regimen in neonates treated with extracorporeal membrane oxygenation

  Start of ECMO 0 hours 24 hours 48 hours 72 hours
Renal function      
   ◦ Creatinine (μmol/l) 35 (19–106) 29.5 (19–106) 40.5 1(6–131) 44 (22–112) 23 (20–41)
   ◦ BUN (mmol/l) 2.05 (1.1–3.8) 2.2 (1.1–3.8) 3.7 (0.9–8) 6 (0.9–7.1) 2.1 (1.5–6)
   ◦ Albumin (g/l) 24 (19–27) 26 (23–35) 28 (25–34) 28 (25–31) 29 (27–29)
Acid-base balance      
   ◦ pH 7.3 (6.97–7.47) 7.4 (7.24–7.47) 7.42 (7.38–7.48) 7.48 (7.43–7.6) 7.47 (7.45–7.67)
   ◦ Bicarbonate level (mmol/l) 22.2 (17.4–33.5) 24.2 (17.4–33.5) 29.8 (23.4–35.2) 31.8 (23.8–35.1) 33.9 (26.3–36.5)
   ◦ Base excess -4 (-12 to 9) 1 (-9 to 9) 5 (-1 to 10) 7 (1–10) 8 (3–14)
Serum electrolytes      
   ◦ Sodium (mmol/l) 140 (138–147) 142 (136–147) 136 (132–142) 135 (133–143) 134 (132–141)
   ◦ Potassium (mmol/l) 3.3 (3.1–4.1) 3.3 (2.8–5.4) 3.85 (3.2–6.2) 3.6 (3.1–4.1) 3.9 (3.5–5.7)
   ◦ Chloride (mmol/l) 106.5 (104–109) 104 (104–104) 102 (100–112) 95 (92–98) 99 (95–107)
  1. Data presented as the median (range). ECMO, extracorporeal membrane oxygenation.