Table 1 Patient characteristics
Patient | Age | Sex | Diagnosis | Outcome | Medication other than pentobarbital | Duration of barbiturate coma | Maximum barbiturate blood level |
|---|---|---|---|---|---|---|---|
1 | 4 months | Male | GCSE after asphyxia | P | Midazolam, valproic acid | 9 days | 20 mg/l (day 2) |
2 | 3 years | Male | GCSE due to Lennox-Gastaut syndrome | M | Lamotrigine, topiramate, valproic acid | 3 days | 37 mg/l (day 3) |
3 | 3.5 years | Female | GCSE due to viral encephalitis | D | Midazolam, carbamazepine, phenytoin, topiramate | 14 days | 70 mg/l (day 12) |
4 | 11 years | Male | TBI (hit by baseball bat) | D | Propofol | 5 days | - |
5 | 12 years | Female | GCSE next to mental retardation | D | Midazolam | 2 days | 193 mg/l (day 7) |
6 | 12 years | Male | GCSE due to viral encephalitis | D | Valproic acid, midazolam | >3 weeks | 83 mg/l (day 6) |
7 | 15 years | Male | TBI (hit by car) | F | Midazolam, morphine, propofol, fentanyl | 16 hours | 54 mg/l (day 2) |
8 | 15 years | Male | TBI (hit by car) | M | Morphine | 23 hours | 47 mg/l (day 2) |