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Table 1 Patient characteristics

From: Continuous noninvasive monitoring of barbiturate coma in critically ill children using the Bispectral™ index monitor

Patient Age Sex Diagnosis Outcome Medication other than pentobarbital Duration of barbiturate coma Maximum barbiturate blood level
1 4 months Male GCSE after asphyxia P Midazolam, valproic acid 9 days 20 mg/l (day 2)
2 3 years Male GCSE due to Lennox-Gastaut syndrome M Lamotrigine, topiramate, valproic acid 3 days 37 mg/l (day 3)
3 3.5 years Female GCSE due to viral encephalitis D Midazolam, carbamazepine, phenytoin, topiramate 14 days 70 mg/l (day 12)
4 11 years Male TBI (hit by baseball bat) D Propofol 5 days -
5 12 years Female GCSE next to mental retardation D Midazolam 2 days 193 mg/l (day 7)
6 12 years Male GCSE due to viral encephalitis D Valproic acid, midazolam >3 weeks 83 mg/l (day 6)
7 15 years Male TBI (hit by car) F Midazolam, morphine, propofol, fentanyl 16 hours 54 mg/l (day 2)
8 15 years Male TBI (hit by car) M Morphine 23 hours 47 mg/l (day 2)
  1. D, death; F, full recovery; GCSE, generalized convulsive status epilepticus; M, minor neurological impairment; P, major neurological impairment; TBI, traumatic brain injury.