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Figure 2 | Critical Care

Figure 2

From: Platelet-derived exosomes induce endothelial cell apoptosis through peroxynitrite generation: experimental evidence for a novel mechanism of septic vascular dysfunction

Figure 2

Electron microscopy reveals the structure of exosomes. Images obtained from the exosome population generated by platelets exposed to diethylamine-NONOate (a) and to thrombin (b) reveal rounded membranaceous structures measuring on average less than 150 nm. It is noteworthy that exosomes from platelets stimulated with diethylamine-NONOate have a more regular surface than those generated by platelets exposed to thrombin. Scale bars, 100 nm; original magnification Ă—60,000.

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