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Table 2 Pulmonary edema assessed by histological measurement of intra-alveolar edema and interstitial (alveolar wall thickness) edema

From: Alveolar instability caused by mechanical ventilation initially damages the nondependent normal lung

 

Nondependent lung

Dependent lung

Positive end-expiratory pressure 10 cmH2O

  

   Intra-alveolar edema

3.22 ± 0.27

3.28 ± 0.25

   Alveolar wall thickness

2.9 ± 0.42

2.72 ± 0.38

Positive end-expiratory pressure 3 cmH2O

  

   Intra-alveolar edema

3.5 ± 0.30

3.7 ± 0.09

   Alveolar wall thickness

2.51 ± 0.45

2.62 ± 0.34

  1. A score for both intra-alveolar and interstitial edema was used to measure edema in both nondependent and dependent lung sections: 0, no edema; 1, mild scattered edema; 2, moderate scattered edema; 3, severe scattered edema; and 4, severe universal edema. Data presented as the mean ± standard error of the mean. No significant difference was seen among groups.
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Critical Care

ISSN: 1364-8535