From: Clinical review: Timing and dose of continuous renal replacement therapy in acute kidney injury
BUN at initiation of RRT (mg/dl) | Survival (%) | |||||||
---|---|---|---|---|---|---|---|---|
Study | Year | Mode of RRT | Study design | N | Early | Late | Early | Late |
Parsons et al. [25] | 1961 | IHD | Retrospective | 33 | 120–150 | >200 | 75 | 12 |
Fisher et al. [26] | 1966 | IHD | Retrospective | 162 | ~150 | >200 | 43 | 26 |
Kleinknecht et al. [27] | 1972 | IHD | Retrospective | 500 | <93 | >163 | 73 | 58 |
Conger [28] | 1975 | IHD | RCT | 18 | <70 | ~150 | 64 | 20 |
Gillum et al. [29] | 1986 | IHD | RCT | 34 | <60 | ~100 | 41 | 53 |
Gettings et al. [31] | 1999 | CRRT | Retrospective | 100 | <60 | >60 | 39 | 20 |
Bouman et al. [12] | 2002 | CRRT | RCT | 106 | LV: 48 (40–66)a | LV: 105 (62–116)a | LV: 69 | LV: 75 |
HV: 46 (38–58)a | HV: 74 | |||||||
Demirkiliç et al. [32] | 2004 | CRRT | Retrospectiveb | 61 | NS | NS | 77 | 45 |
Elahi et al. [33] | 2004 | CRRT | Retrospectiveb | 64 | 67 ± 35c | 75 ± 61c | 78 | 57 |
Piccinni et al. [34] | 2006 | CRRT | Retrospectived | 80 | NS | NS | 55 | 28 |
Liu et al. [35] | 2006 | IHD and CRRT | Observational | 243 | ≤ 76 | >76 | 65 | 59 |